Risk of Post-Traumatic Stress Disorder in 111 survivors the 2009 Viareggio (Italy) Rail Crash: the role of mood spectrum comorbidity

M. Miniati 1 , A. Petracca 2 , C. Carmassi 1 , M. Mauri 1 , S. Fratta 1 , E. Fui1 1 , I.Giunti 1 , C. Gesi 1 , G. Macchia 1 , L. Dell’Osso 2

1 Section of Psychiatry, Department of Clinical and Experimental Medicine, University of Pisa, Italy; 2 Psychiatrist, Viareggio, Italy


To explore the presence of PTSD and the potential correlations between the risk of developing PTSD and the lifetime mood spectrum signs and symptoms, as assessed with the Mood Spectrum Questionnaire Lifetime Version (MOODS-SR), in a sample of survivors of a liquid gas train crash in Italy, in 2009. 


One hundred eleven subjects were assessed with the Structured Clinical Interview for Axis I Disorder (SCID-I), the Mood Spectrum Questionnaire (MOODS-SR) Lifetime version, the Impact of Event Scale-Revised (IES-R), and the Trauma and Loss Spectrum Questionnaire (TALS-SR). 


Sixty-six subjects, of the 111 who completed the SCID-I (59.5%), met criteria for PTSD. PTSD patients showed higher comorbidity rates for Generalized Anxiety Disorder (GAD) (p < 0.001), and lifetime and current Major Depressive Disorder (MDD) (p < 0.001) than subjects who did not develop PTSD. Lifetime MOODS-SR ‘Sociability/Extraversion’ factor and the prevalence of lifetime MDD differentiated subjects with from those without PTSD, when a multiple logistic regression analysis was performed. 


Although further research is needed, our results show a significant correlation between the risk of developing PTSD and the mood spectrum comorbidity.

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