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Psychopathology and Clinical Phenomenology

Vol. 31: Issue 2 - June 2025

Cannabis-Induced Fregoli Syndrome, a Case Report and Literature Review.

Cannabis use and Fregoli syndrome.

Authors

Key words: Cannabis-induced Fregoli syndrome, Cannabis-induced psychosis,, Fregoli syndrome, Capgras syndrome, Delusional misidentification syndromes
Publication Date: 2025-07-31

Abstract

Objective: Fregoli syndrome is already very rare in itself, and even rarer are those syndromes due to a general medical condition or induced by substances. Since a cannabis-induced Fregoli syndrome has never been described, and the author of this article has diagnosed one, not having obtained the patient’s consent to publish his story, he presented it as a starting point, anonymously, taking advantage of the opportunity to write a systematic and complete review on the subject, in an attempt to provide a contribution to the study of this phenomenon but above all to invite scientists to search for other possible cases caused by cannabis. Methods: this work could constitute an interesting review on the psychiatric and neurological nature of the syndrome, but insinuating among researchers who are interested in addictions, the doubt that even a substance of abuse can induce this syndrome. Results: few studies have examined samples of people with cannabis-induced psychotic symptoms;, none of these has investigated the cannabis liability, in particular; the author was able to find a particular case, certainly induced by cannabis. Conclusions: only two articles considered the possibility of an exotoxic etiology in Fregoli syndrome – however excluding it – and only one case report has general characteristics that are comparable to those that will be presented in the current paper, even if it refers to ecstasy and not to cannabis.

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Authors

Giovan Battista Ivan Polichetti - Department of Mental Health and Addiction, Local Health Trust of Romagna, Cesena, Italy

How to Cite
[1]
Polichetti, G.B.I. 2025. Cannabis-Induced Fregoli Syndrome, a Case Report and Literature Review.: Cannabis use and Fregoli syndrome. Journal of Psychopathology. 31, 2 (Jul. 2025).
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