Mood spectrum in patients with endometriosis

Objective

To assess the relationship between endometriosis-related pain, and mood symtoms.

Method

Forty-seven outpatients diagnosed with endometriosis were assessed using the MOODS-SR questionnaire for mood symptoms and VAS score for pain. Statistical analyses included Pearson’s correlation coefficient (r) and linear regression models.

Results

Dyspareunia correlated positively with depressive mood (p = . 020), energy in depressive (p = . 002) and manic (p = . 045) states, cognition in depressive states (p = . 028), and rhythmicity (p = . 001). Chronic pelvic pain correlated with depressive mood (p = . 003), energy (p < .001) and cognition (p = . 005) in depressive states and rhythmicity (p = . 016). Linear regression models demonstrated dyspareunia’s predictive relationship with depressive mood (p = . 020), energy levels during depressive (p = . 002) and manic (p = . 045) states, cognitive dysfunction during depressive phases (p = . 028) and rhythmicity (p = . 001). Chronic pelvic pain was correlated with depressive mood (p = . 003), energy level (p < . 001) and cognitive dysfunction (p = . 005) in depressive states, and rhythmicity (p = . 016).

Conclusion

The study suggests an association between dyspareunia, chronic pelvic pain and mood disturbances emphasizing the necessity for a multidisciplinary approach to endometriosis management that considers mental health of patients.